EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia

Haematologica. 2014 Nov;99(11):e225-7. doi: 10.3324/haematol.2014.107128. Epub 2014 Jul 11.
No abstract available

Keywords: EVI1; MLL; acute myeloid leukemia; pediatrics; prognostic factor.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA-Binding Proteins / genetics*
  • Gene Expression*
  • Gene Rearrangement*
  • Histone-Lysine N-Methyltransferase
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / mortality*
  • Leukemia, Myeloid, Acute / pathology
  • MDS1 and EVI1 Complex Locus Protein
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Prognosis
  • Proto-Oncogenes / genetics*
  • Transcription Factors / genetics*
  • Translocation, Genetic

Substances

  • DNA-Binding Proteins
  • KMT2A protein, human
  • MDS1 and EVI1 Complex Locus Protein
  • MECOM protein, human
  • Transcription Factors
  • Myeloid-Lymphoid Leukemia Protein
  • Histone-Lysine N-Methyltransferase