Optical diagnostic techniques for use in lesions of the head and neck: review of the latest developments

Ben Green; Alistair R M Cobb; Peter A Brennan; Colin Hopper

doi:10.1016/j.bjoms.2014.06.010

Optical diagnostic techniques for use in lesions of the head and neck: review of the latest developments

Br J Oral Maxillofac Surg. 2014 Oct;52(8):675-80. doi: 10.1016/j.bjoms.2014.06.010. Epub 2014 Jul 8.

Authors

Ben Green¹, Alistair R M Cobb², Peter A Brennan³, Colin Hopper⁴

Affiliations

¹ Craniofacial Unit, Great Ormond Street Hospital for Children, London, UK; King's College London School of Medicine, Guy's Campus, London, UK. Electronic address: ben.c.green@kcl.ac.uk.
² South-West Cleft Unit & Department of Oral and Maxillofacial Surgery, North Bristol NHS Trust, Bristol, UK.
³ Department of Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, UK.
⁴ Head & Neck Unit, University College London Hospital, London, UK.

PMID: 25015019
DOI: 10.1016/j.bjoms.2014.06.010

Abstract

Optical biopsy systems are a potential adjunct to the histopathological assessment of tissue specimens; they are not invasive and can give an immediate result. We review the most common optical biopsy techniques used to detect lesions of the head and neck: elastic scattering spectroscopy, microendoscopy, narrow band imaging, fluorescence, and optical coherence tomography, and discuss their clinical use.

Keywords: elastic scattering spectroscopy; fluorescence; microendoscopy; narrow-band imaging; optical biopsy; optical coherence tomography; oral cancer; skin cancer.

Publication types

Review

MeSH terms

Biopsy / methods
Elasticity Imaging Techniques
Endoscopy / methods
Head and Neck Neoplasms / diagnosis*
Head and Neck Neoplasms / pathology
Humans
Optical Imaging / methods*
Precancerous Conditions / diagnosis*
Precancerous Conditions / pathology
Spectrum Analysis / methods