Psychiatric morbidity in asymptomatic human immunodeficiency virus patients

V S Chauhan; Suprakash Chaudhury; S Sudarsanan; Kalpana Srivastava

doi:10.4103/0972-6748.132925

Psychiatric morbidity in asymptomatic human immunodeficiency virus patients

Ind Psychiatry J. 2013 Jul;22(2):125-30. doi: 10.4103/0972-6748.132925.

Authors

V S Chauhan¹, Suprakash Chaudhury², S Sudarsanan¹, Kalpana Srivastava¹

Affiliations

¹ Department of Psychiatry, Armed Forces Medical College, Pune, Maharashtra, India.
² Department of Psychiatry, Pravara Institute of Medical Sciences (Deemed University), Rural Medical College, Loni, District Ahmednagar, Maharashtra, India.

Abstract

Background: Psychiatric morbidity in human immunodeficiency virus (HIV) patients is being studied all over the world. There is paucity of Indian literature particularly in asymptomatic HIV individuals.

Aim: The aim of the following study is to establish the prevalence and the determinants of psychiatric morbidity in asymptomatic HIV patients.

Materials and methods: A cross-sectional study was undertaken to assess psychiatric morbidity as per ICD-10 dacryocystorhinostomy criteria in 100 consecutive asymptomatic seropositive HIV patients and an equal number of age, sex, education, economic and marital status matched HIV seronegative control. All subjects were assessed with the general health questionnaire (GHQ), mini mental status examination, hospital anxiety and depression scale (HADS) and sensation seeking scale (SSS) and the scores were analyzed statistically.

Results: Asymptomatic HIV positive patients had significantly higher GHQ caseness and depression but not anxiety on HADS as compared to HIV seronegative controls. On SSS asymptomatic HIV seropositive subjects showed significant higher scores in thrill and adventure seeking, experience seeking and boredom susceptibility as compared to controls. HIV seropositive patients had significantly higher incidence of total psychiatric morbidity. Among the individual disorders, alcohol dependence syndrome, sexual dysfunction and adjustment disorder were significantly increased compared with HIV seronegative controls.

Conclusion: Psychiatric morbidity is higher in asymptomatic HIV patients when compared to HIV seronegative controls. Among the individual disorders, alcohol dependence syndrome, sexual dysfunction and adjustment disorder were significantly increased compared with HIV seronegative controls. High sensation seeking and substance abuse found in HIV seropositive patients may play a vital role in engaging in high-risk behavior resulting in this dreaded illness.

Keywords: Acquired immune deficiency syndrome; anxiety; depression; human immunodeficiency virus; psychiatric morbidity; sensation seeking; substance abuse.