The interplay between radiation and the immune system in the field of post-radical pneumonitis and fibrosis and why it is important to understand it

Pelagia G Tsoutsou

doi:10.1517/14656566.2014.938049

The interplay between radiation and the immune system in the field of post-radical pneumonitis and fibrosis and why it is important to understand it

Expert Opin Pharmacother. 2014 Sep;15(13):1781-3. doi: 10.1517/14656566.2014.938049. Epub 2014 Jul 10.

Author

Pelagia G Tsoutsou¹

Affiliation

¹ Radiation Oncologist, Médecin Adjointe, Hôpital du Valais (RSV) - Centre Hospitalier du Valais Romand (CHVR), Hôpital de Sion, Service de Radio-Oncologie , Av. du Grand-Champsec 80, Case postale 736, CH-1951 Sion , Switzerland +027 603 87 15 ; +027 603 45 06 ; pauletta24@hotmail.com.

PMID: 25010533
DOI: 10.1517/14656566.2014.938049

Abstract

A discussion on the importance and pathogenesis of radiation-induced pneumonitis and fibrosis is provided, with a special focus on the role of the immune system. The need to understand this interaction is highlighted in view of emerging therapeutic potential.

Keywords: cytokines; immune system; radiation fibrosis; radiation pneumonitis.

Publication types

Editorial

MeSH terms

Humans
Immune System
Lung Neoplasms / immunology
Lung Neoplasms / radiotherapy
Pulmonary Fibrosis / etiology
Pulmonary Fibrosis / immunology*
Pulmonary Fibrosis / therapy
Radiation Pneumonitis / etiology
Radiation Pneumonitis / immunology*
Radiation Pneumonitis / therapy