Squamous cell carcinoma of the superior gingivobuccal sulcus: an 11-year institutional experience of 203 cases

Jpn J Clin Oncol. 2014 Sep;44(9):807-11. doi: 10.1093/jjco/hyu088. Epub 2014 Jul 9.

Abstract

Objective: The report presents an 11-year Institutional experience of 203 cases with superior gingivobuccal sulcus tumours receiving surgical intervention at a comprehensive tertiary cancer care centre.

Methods: A retrospective chart review of patients with a confirmed diagnosis of squamous cell carcinoma of superior gingivobuccal sulcus was done and data related to patient demographic profile; details of surgical procedure, follow-up and survival were collected.

Results: Infratemporal fossa clearance was performed in 56 patients. The 10-year overall survival and disease-free survival was observed to be 39 and 52%, respectively, with a median follow-up of 15 months. The overall survival was 40 and 36%, respectively, in cases with and without infratemporal fossa clearance. Similarly, the disease-free survival was found to be 58 and 49%, respectively, in cases with and without infratemporal fossa clearance.

Conclusion: Patients with higher stage tumours who underwent infratemporal fossa clearance showed better overall and disease-free survival than those who did not undergo infratemporal fossa clearance.

Keywords: infratemporal fossa clearance; reconstruction; squamous cell carcinoma; superior gingivobuccal sulcus; survival.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / therapy*
  • Cheek / pathology
  • Cheek / surgery
  • Chemotherapy, Adjuvant
  • Disease-Free Survival
  • Female
  • Gingival Neoplasms / pathology
  • Gingival Neoplasms / therapy
  • Humans
  • India / epidemiology
  • Kaplan-Meier Estimate
  • Male
  • Mastication
  • Medical Records
  • Middle Aged
  • Mouth Neoplasms / epidemiology
  • Mouth Neoplasms / pathology*
  • Mouth Neoplasms / therapy*
  • Neoplasm Staging
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Smoking / adverse effects
  • Treatment Outcome