Changing the core of transcription

Elife. 2014 Jul 8:3:e03575. doi: 10.7554/eLife.03575.

Abstract

Different members of the TAF family of proteins work in differentiated cells, such as motor neurons or brown fat cells, to control the expression of genes that are specific to each cell type.

Keywords: TBP-associated factor TAF; motor neurons; neuronal enhancers; neuronal gene expression; stem cells; transcription factors.

Publication types

  • Comment

MeSH terms

  • Animals
  • Gene Expression Regulation, Developmental*
  • Motor Neurons / metabolism*
  • Promoter Regions, Genetic*
  • TATA-Binding Protein Associated Factors / metabolism*
  • Transcription Factor TFIID / metabolism*

Substances

  • TATA-Binding Protein Associated Factors
  • Transcription Factor TFIID