High throughput screening for biomaterials discovery

J Control Release. 2014 Sep 28:190:115-26. doi: 10.1016/j.jconrel.2014.06.045. Epub 2014 Jun 30.

Abstract

Using microarray technologies thousands of biomedical materials can be screened in a rapid, parallel and cost effective fashion to identify the optimum candidate that fulfils a specific biomedical application. High throughput surface characterization (HTSC) of printed microarrays has played a key role in the discovery and development of biomedical materials. This review focuses on the production and HTSC of microarrays, their application in specific biomedical fields and a future perspective on the development of this technology.

Keywords: Biomedical materials; High throughput surface characterization (HTSC); Microarray.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials*
  • Biomedical Research
  • Drug Carriers
  • Drug Discovery / methods*
  • High-Throughput Screening Assays / methods*
  • Humans
  • Microarray Analysis*
  • Polymers
  • Stem Cells

Substances

  • Biocompatible Materials
  • Drug Carriers
  • Polymers