Bioactive peptides from meat muscle and by-products: generation, functionality and application as functional ingredients

Meat Sci. 2014 Oct;98(2):227-39. doi: 10.1016/j.meatsci.2014.05.036. Epub 2014 Jun 8.

Abstract

Bioactive peptides are sequences of between 2-30 amino acids in length that impart a positive health effect to the consumer when ingested. They have been identified from a range of foods, including milk and muscle sources including beef, chicken, pork and marine muscles. The myriad of peptides identified from these sources have known antihypertensive, opioid, antioxidant, antithrombotic and other bioactivities. Indeed, bioactive peptides could play a role in the prevention of diseases associated with the development of metabolic syndrome and mental health diseases. The aim of this work is to present an overview of the bioactive peptides identified in muscle proteins and by-products generated during the processing of meat. The paper looks at the isolation, enrichment and characterisation strategies that have been employed to date to generate bioactive peptides and the potential future applications of these peptides in functional foods for the prevention of heart and mental health problems and obesity.

Keywords: ACE-I; Bioactive peptides; Blood; Meat by-products; Mental health; PEP.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification
  • Anti-Infective Agents / pharmacology
  • Antihypertensive Agents / chemistry
  • Antihypertensive Agents / isolation & purification
  • Antihypertensive Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Cattle
  • Chickens
  • Fibrinolytic Agents / chemistry
  • Fibrinolytic Agents / isolation & purification
  • Fibrinolytic Agents / pharmacology
  • Meat / analysis*
  • Metabolic Syndrome / prevention & control
  • Muscle Proteins / chemistry
  • Muscle, Skeletal / chemistry*
  • Peptides / chemistry
  • Peptides / isolation & purification*
  • Peptides / pharmacology*
  • Swine

Substances

  • Anti-Infective Agents
  • Antihypertensive Agents
  • Antioxidants
  • Fibrinolytic Agents
  • Muscle Proteins
  • Peptides