Irinotecan pharmacogenetics: a finished puzzle?

J Clin Oncol. 2014 Aug 1;32(22):2287-9. doi: 10.1200/JCO.2014.56.3387. Epub 2014 Jun 23.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Antineoplastic Agents, Phytogenic / administration & dosage*
  • Antineoplastic Agents, Phytogenic / pharmacokinetics*
  • Camptothecin / administration & dosage
  • Camptothecin / analogs & derivatives*
  • Camptothecin / pharmacokinetics
  • Glucuronosyltransferase / genetics*
  • Humans
  • Irinotecan
  • Male
  • Neoplasms / drug therapy*

Substances

  • Antineoplastic Agents, Phytogenic
  • Irinotecan
  • UGT1A1 enzyme
  • Glucuronosyltransferase
  • Camptothecin