The relationship of early-life antibiotic use with asthma in at-risk children

J Allergy Clin Immunol. 2014 Sep;134(3):728-9. doi: 10.1016/j.jaci.2014.05.006. Epub 2014 Jun 19.

Abstract

Asthma prevalence has increased with the reason remaining unknown. Antibiotics early in life have been hypothesized as playing a role in the development of asthma; however, we have found the relationship may be due to confounding by respiratory infections and may not be causally related.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Asthma / etiology
  • Asthma / immunology*
  • Child, Preschool
  • Female
  • Humans
  • Hygiene Hypothesis*
  • Infant
  • Infant, Newborn
  • Male
  • Patient Education as Topic
  • Pregnancy
  • Prospective Studies
  • Respiratory Tract Infections / complications
  • Respiratory Tract Infections / drug therapy*
  • Risk
  • Urban Population*

Substances

  • Anti-Bacterial Agents