Accuracy of MR in growth plate measurement

Skeletal Radiol. 2014 Sep;43(9):1263-9. doi: 10.1007/s00256-014-1911-9. Epub 2014 Jun 20.

Abstract

Purpose: To analyze the accuracy of growth-plate thickness measurements detected on 1.5-T and 7-T MR images using histology sections as a standard of reference.

Materials and methods: Four defrosted pig tibiae were 1.5-T MR scanned and one fresh tibia was 7-T MR scanned. The height of the growth plate was measured and compared to histology.

Results: Histology measurements showed a mean growth plate thickness of 467 μm (SD = 82.2). The mean growth plate thickness measured in the 7-T MR images was 465 μm (SD = 62.2) and 1,325 μm (SD = 183.5) on 1.5-T MR measurements. We found a better correspondence between the growth plate thickness measured on the 7-T MR and histology samples compared to 1.5 T.

Conclusions: The growth plate can be identified and measured with high accuracy using 7-T MR. 1.5-T MR can only describe some morphological characteristics.

MeSH terms

  • Animals
  • Growth Plate / anatomy & histology*
  • Image Interpretation, Computer-Assisted / methods*
  • In Vitro Techniques
  • Magnetic Resonance Imaging / methods*
  • Observer Variation
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Swine
  • Tibia / anatomy & histology*