[Optimal cut-off value of phalangeal radiographic absorptiometry to identify osteoporosis in postmenopausal women]

Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 May;45(3):506-8, 528.
[Article in Chinese]

Abstract

Objective: To study the optimal cut-off value of phalangeal radiographic absorptiometry (RA) to identify osteoporosis in postmenopausal women.

Methods: A total of 650 postmenopausal women were recruited in this study. Bone mineral density (BMD) at lumbar spine and left proximal femur neck was measured by dual-energy X-ray absorptiometry (DXA) as the standard method to identify postmenopausal osteoprosis. Phalangeal bone density was estimated by the use of RA. Optimal cut-off value of phalangeal RA was determined using a ROC curve for screening the ostreoporosis cases.

Results: When the cut-off value of phalangeal RA was T score < or = -2.5, the sensitivity was 74.2%, the specificity was 72.9%. When the cut-off value was T score < or = -2.21, the sensitivity was 81.4%, the specificity was 62.0%.

Conclusion: The cut-off value of phalangeal RA as T score -2.21. which has higher sensitivity could be optimal to identify postmenopausal osteoporosis.

MeSH terms

  • Absorptiometry, Photon*
  • Bone Density
  • Female
  • Finger Phalanges / pathology*
  • Hip Joint
  • Humans
  • Lumbar Vertebrae
  • Osteoporosis, Postmenopausal / diagnosis*
  • ROC Curve
  • Reference Values
  • Sensitivity and Specificity