An F-18-FDG-PET study of a pair of monozygotic twins with recent-onset schizophrenia revealed a higher index of metabolic asymmetry (IA) in the medial and posterior thalamus in both cases. Some questions regarding the influence of neuroleptic treatment and handedness on metablic patterns and the role of the thalamus in schizophrenia are discussed in the light of recent studies.
Keywords: deoxyglucose metabolism; schizophrenia; thalamus physiopathology; twins psychology.