Innate lymphoid cells: of precursors and products…

Nicolas Serafini; Wei Xu; James P Di Santo

doi:10.1016/j.cub.2014.05.010

Innate lymphoid cells: of precursors and products…

Curr Biol. 2014 Jun 16;24(12):R573-R576. doi: 10.1016/j.cub.2014.05.010.

Authors

Nicolas Serafini¹, Wei Xu¹, James P Di Santo²

Affiliations

¹ Innate Immunity Unit, Institut Pasteur, Paris, France; INSERM U668, Paris, France.
² Innate Immunity Unit, Institut Pasteur, Paris, France; INSERM U668, Paris, France. Electronic address: james.di-santo@pasteur.fr.

PMID: 24937286
DOI: 10.1016/j.cub.2014.05.010

Abstract

Recent reports have identified committed innate lymphoid cell (ILC) precursors and tissue-resident ILC subsets that have unique functional attributes. Taken together, these studies provide a framework for understanding how distinct ILCs are generated during hematopoiesis and further suggest additional parallels between models of ILC and T helper cell differentiation.