First reported case of interferon-alpha-induced sarcoidosis in an Asian patient with malignant melanoma

Eun Kyoung Jeon; Jihyoung Hong; Sook Hee Hong; Ji Young Kang; Gyeongsin Park; Myeong Im Ahn; Jun Young Lee; Jinhyoung Kang

doi:10.1111/ajco.12204

First reported case of interferon-alpha-induced sarcoidosis in an Asian patient with malignant melanoma

Asia Pac J Clin Oncol. 2016 Jun;12(2):e347-e349. doi: 10.1111/ajco.12204. Epub 2014 Jun 17.

Authors

Eun Kyoung Jeon¹, Jihyoung Hong¹, Sook Hee Hong¹, Ji Young Kang², Gyeongsin Park³, Myeong Im Ahn⁴, Jun Young Lee⁵, Jinhyoung Kang¹

Affiliations

¹ Division of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
² Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
³ Department of Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
⁴ Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
⁵ Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

PMID: 24935527
DOI: 10.1111/ajco.12204

Abstract

Anticancer agents can induce sarcoidosis. Interferon-alpha, which is used for the treatment of malignant melanoma and renal cell cancer, is one causative agent of sarcoidosis. However, there are few reports of interferon-alpha-induced sarcoidosis in patients with malignant melanoma. Clinically, it is important to consider the possibility of sarcoidosis in such patients because it could be easily regarded as a metastatic lesion due to underlying malignancy and given unnecessary treatment. Here, we report on the first case of interferon-alpha-induced sarcoidosis in an Asian melanoma patient.

Publication types

Case Reports