A colorimetric and luminescent dual-modal assay for Cu(II) ion detection using an iridium(III) complex

Dik-Lung Ma; Hong-Zhang He; Daniel Shiu-Hin Chan; Chun-Yuen Wong; Chung-Hang Leung

doi:10.1371/journal.pone.0099930

A colorimetric and luminescent dual-modal assay for Cu(II) ion detection using an iridium(III) complex

PLoS One. 2014 Jun 13;9(6):e99930. doi: 10.1371/journal.pone.0099930. eCollection 2014.

Authors

Dik-Lung Ma¹, Hong-Zhang He¹, Daniel Shiu-Hin Chan¹, Chun-Yuen Wong², Chung-Hang Leung³

Affiliations

¹ Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
² Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, People's Republic of China.
³ State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.

Abstract

A novel iridium(III) complex-based chemosensor bearing the 5,6-bis(salicylideneimino)-1,10-phenanthroline ligand receptor was developed, which exhibited a highly sensitive and selective color change from colorless to yellow and a visible turn-off luminescence response upon the addition of Cu(II) ions. The interactions of this iridium(III) complex with Cu2+ ions and thirteen other cations have been investigated by UV-Vis absorption titration, emission titration, and 1H NMR titration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Colorimetry / methods*
Copper / analysis*
Copper / chemistry
Iridium / chemistry*
Luminescent Measurements / methods*

Substances

Iridium
Copper

Grants and funding

This work is supported by Hong Kong Baptist University (FRG2/12-13/021 and FRG2/13-14/008), the Centre for Cancer and Inflammation Research, the School of Chinese Medicine (CCIR-SCM, HKBU), the Health and Medical Research Fund (HMRF/13121482), the Research Grants Council (HKBU/201811, HKBU/204612, and HKBU/201913), the French National Research Agency/Research Grants Council Joint Research Scheme (A-HKBU201/12), the Science and Technology Development Fund, Macao SAR (103/2012/A3) and the University of Macau (MYRG091(Y3-L2)-ICMS12-LCH, MYRG121(Y3-L2)-ICMS12-LCH, MRG007/LCH/2014/ICMS and MRG023/LCH/2013/ICMS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.