Validation of a numerical FSI simulation of an aortic BMHV by in vitro PIV experiments

Med Eng Phys. 2014 Aug;36(8):1014-23. doi: 10.1016/j.medengphy.2014.05.004. Epub 2014 Jun 10.

Abstract

In this paper, a validation of a recently developed fluid-structure interaction (FSI) coupling algorithm to simulate numerically the dynamics of an aortic bileaflet mechanical heart valve (BMHV) is performed. This validation is done by comparing the numerical simulation results with in vitro experiments. For the in vitro experiments, the leaflet kinematics and flow fields are obtained via the particle image velocimetry (PIV) technique. Subsequently, the same case is numerically simulated by the coupling algorithm and the resulting leaflet kinematics and flow fields are obtained. Finally, the results are compared, revealing great similarity in leaflet motion and flow fields between the numerical simulation and the experimental test. Therefore, it is concluded that the developed algorithm is able to capture very accurately all the major leaflet kinematics and dynamics and can be used to study and optimize the design of BMHVs.

Keywords: BMHV; Experiment; FSI; Numerical simulation; PIV; Validation.

Publication types

  • Validation Study

MeSH terms

  • Algorithms
  • Aorta / physiology
  • Aortic Valve* / physiology
  • Biomechanical Phenomena
  • Blood Flow Velocity / physiology
  • Computer Simulation*
  • Heart Rate / physiology
  • Heart Valve Prosthesis*
  • Humans
  • In Vitro Techniques
  • Models, Cardiovascular*
  • Rheology
  • Stroke Volume / physiology