A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

Chem Commun (Camb). 2014 Jul 28;50(59):8073-6. doi: 10.1039/c4cc03190c.

Abstract

An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0-5 °C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry*
  • Molecular Structure
  • Pyridazines / chemical synthesis*
  • Pyridazines / chemistry
  • Quantum Theory
  • Salts / chemistry

Substances

  • Azo Compounds
  • Pyridazines
  • Salts