Analysis of a bioregulator isolated from rat testes in roller organotypic culture of mouse testes in vitro

M S Krasnov; V P Yamskova; B B Berezin; N V Yamskova; I A Yamskov

doi:10.1007/s10517-014-2517-x

Analysis of a bioregulator isolated from rat testes in roller organotypic culture of mouse testes in vitro

Bull Exp Biol Med. 2014 May;157(1):172-5. doi: 10.1007/s10517-014-2517-x. Epub 2014 Jun 11.

Authors

M S Krasnov¹, V P Yamskova, B B Berezin, N V Yamskova, I A Yamskov

Affiliation

¹ A. N. Nesmeyanov Institute of Elementorganic Compounds, Russian Academy of Sciences, Moscow, Russia, embrmsk@mail.ru.

PMID: 24913585
DOI: 10.1007/s10517-014-2517-x

Abstract

A new bioregulator, a representative of membranotropic homeostatic tissue-specific bioregulators acting in ultralow doses, was isolated from rat testes. A model of roller organotypic culturing of mouse testes was developed and the protective effect of the bioregulator was analyzed.

MeSH terms

Animals
Biological Factors / isolation & purification
Biological Factors / pharmacology*
Cell Survival / drug effects
Chromatography, Reverse-Phase
Histocytochemistry
Liver / drug effects*
Liver / ultrastructure
Male
Mice
Protective Agents / isolation & purification
Protective Agents / pharmacology*
Rats
Testis / chemistry*
Testis / drug effects*
Testis / ultrastructure
Tissue Culture Techniques

Substances

Biological Factors
Protective Agents