Single institution and statewide performance of ultrasound in diagnosing appendicitis in pregnancy

J Matern Fetal Neonatal Med. 2015 Apr;28(6):727-33. doi: 10.3109/14767058.2014.932344. Epub 2014 Jul 2.

Abstract

Objective: Assess the performance of ultrasound (US) in pregnant patients presenting with acute abdominal pain concerning for appendicitis.

Methods: Descriptive analysis of pregnant patients who underwent an US for acute abdominal pain over a 6-year period using data from a statewide quality improvement collaborative and a single center.

Results: Statewide, 131 pregnant patients underwent an appendectomy and 85% had an US. In our single-center case series, 49 pregnant patients underwent an US for acute abdominal pain and four patients had appendicitis (8%). Of those, three were definitively diagnosed with US. The appendix was visualized by US in five patients (3 appendicitis/2 normal). Mean gestational age was 11 weeks for visualization of the appendix versus 20 weeks for non-visualization (p < 0.001). Concordance between US and pathology was similar statewide and at our institution (43%).

Conclusions: US appears to play a central role in the evaluation of appendicitis in pregnant women, especially in the first trimester, and often contributes to definitive disposition. US performed less well in excluding appendicitis; however, in certain clinical settings, providers appeared to trust US findings. From these results, we developed a multidisciplinary imaging pathway for pregnant patients who present with acute abdominal pain concerning for appendicitis.

Keywords: Appendicitis; diagnostic imaging; pregnancy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abdomen, Acute / diagnostic imaging
  • Abdomen, Acute / epidemiology
  • Abdomen, Acute / etiology
  • Adolescent
  • Adult
  • Appendectomy / statistics & numerical data
  • Appendicitis / diagnostic imaging*
  • Appendicitis / epidemiology
  • Appendicitis / surgery
  • Female
  • Humans
  • Predictive Value of Tests
  • Pregnancy
  • Pregnancy Complications / diagnostic imaging*
  • Pregnancy Complications / epidemiology
  • Pregnancy Complications / surgery
  • Retrospective Studies
  • Ultrasonography, Prenatal* / standards
  • Young Adult