SnapShot: resident memory T cells

Lalit K Beura; David Masopust

doi:10.1016/j.cell.2014.05.026

SnapShot: resident memory T cells

Cell. 2014 Jun 5;157(6):1488-1488.e1. doi: 10.1016/j.cell.2014.05.026.

Authors

Lalit K Beura¹, David Masopust¹

Affiliation

¹ Department of Microbiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

PMID: 24906159
DOI: 10.1016/j.cell.2014.05.026

Abstract

Resident memory T cells (TRM) comprise a subset of nonrecirculating memory T cells that remain positioned at common portals of reinfection. These include barrier tissues such as the mucosae and skin. TRM orchestrate the initial response to pathogens re-encountered at these locales, thereby accelerating protective immune responses.

MeSH terms

Animals
Humans
Immunologic Memory*
T-Lymphocytes / cytology
T-Lymphocytes / immunology*