Vivid tumor imaging utilizing liposome-carried bimodal radiotracer

ACS Med Chem Lett. 2014 Feb 4;5(4):390-4. doi: 10.1021/ml400513g. eCollection 2014 Apr 10.

Abstract

By developing a new bimodal radioactive tracer that emits both luminescence and nuclear signals, a trimodal liposome for optical, nuclear, and magnetic resonance imaging is efficiently prepared. Fast clearance of the radiotracer from reticuloendothelial systems enables vivid tumor imaging with minimum background.

Keywords: Cerenkov radiation; Imaging agent; liposome; multimodal imaging; radiopharmaceutical.