Osteonecrosis Mimicking Bone Metastasis in Femoral Head on (18)F-FDG PET/CT: A Case Report

Nucl Med Mol Imaging. 2011 Mar;45(1):68-71. doi: 10.1007/s13139-010-0060-x. Epub 2010 Nov 11.

Abstract

A 77-year-old woman underwent chemotherapy, radiotherapy, and brachytherapy for cervical cancer 9 years ago. On a follow-up (18)F-fluorodeoxyglucose (FDG) PET/CT image, focal FDG uptake was noted in a focal osteolytic lesion in the right femoral head. During magnetic resonance imaging, this lesion showed subchondral dark-signal-intensity rim on T1-weighted image and double line sign on T2-weighted image, suggestive of osteonecrosis. The lesion was pathologically confirmed as osteonecrosis after surgery. This case demonstrates that osteonecrosis of the femoral head may demonstrate focal FDG uptake mimicking bone metastasis.

Keywords: 18F-fluorodeoxyglucose; Avascular necrosis; Bone metastasis; Femoral head; Positron emission tomography/computed tomography.