A new coumarin from Calophyllum hosei

Nat Prod Res. 2014;28(19):1534-8. doi: 10.1080/14786419.2014.924001. Epub 2014 Jun 4.

Abstract

A new coumarin, hoseimarin (1), together with four other xanthones, trapezifolizanthone (2), osajaxanthone (3), β-mangostin (4) and caloxanthone A (5), were isolated from the stem bark of Calophyllum hosei. The structures of these compounds were established by using spectroscopic analysis which included (1)H NMR, (13)C NMR, COSY, DEPT, HMQC and HMBC experiments.

Keywords: Calophyllum hosei; coumarin; hoseimarin; trapezifolixanthone.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / isolation & purification*
  • Anti-Inflammatory Agents / pharmacology
  • Calophyllum / chemistry*
  • Coumarins / chemistry
  • Coumarins / isolation & purification*
  • Coumarins / pharmacology
  • Isoflavones / chemistry
  • Isoflavones / isolation & purification
  • Lipopolysaccharides / pharmacology
  • Macrophages / drug effects
  • Mice
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Bark / chemistry
  • Plants, Medicinal / chemistry*
  • Xanthones / chemistry
  • Xanthones / isolation & purification

Substances

  • Anti-Inflammatory Agents
  • Coumarins
  • Isoflavones
  • Lipopolysaccharides
  • Xanthones
  • hoseimarin
  • osajaxanthone
  • mangostin