Introduction: MicroRNAs in human reproduction: small molecules with crucial regulatory roles

Tal Imbar; Daniela Galliano; Antonio Pellicer; Neri Laufer

doi:10.1016/j.fertnstert.2014.04.030

Introduction: MicroRNAs in human reproduction: small molecules with crucial regulatory roles

Fertil Steril. 2014 Jun;101(6):1514-5. doi: 10.1016/j.fertnstert.2014.04.030.

Authors

Tal Imbar¹, Daniela Galliano², Antonio Pellicer³, Neri Laufer⁴

Affiliations

¹ IVF Unit and The Magda and Richard Hoffman Center for Human Placenta Research, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Mount Scopus, Jerusalem, Israel. Electronic address: talim@hadassah.org.il.
² Division of Reproductive Medicine, Instituto Valeciano de Infertilidad, Barcelona, Spain.
³ Instituto Valenciano de Infertilidad and Instituto Universitario IVI, Valencia University, Valencia, Spain; Department of Obstetrics and Gynecology, Valencia University school of Medicine, Valencia, Spain.
⁴ Reproductive Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

PMID: 24882615
DOI: 10.1016/j.fertnstert.2014.04.030

Abstract

MicroRNAs constitute a large family of approximately 21-nucleotide-long, noncoding RNAs. They emerged more than 20 years ago as key posttranscriptional regulators of gene expression. The regulatory role of these small RNA molecules has recently begun to be explored in the human reproductive system. In this issue's Views and Reviews, the authors present the current knowledge regarding the involvement of microRNAs in several aspects of human reproduction and discuss its future implications for clinical practice.

Keywords: microRNA; reproduction.

Publication types

Introductory Journal Article
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Female
Fertility* / genetics
Gene Expression Regulation, Developmental*
Humans
Infertility / genetics
Infertility / physiopathology
Infertility / therapy
Male
MicroRNAs / metabolism*
Pregnancy
Reproduction* / genetics
Reproductive Techniques, Assisted
Signal Transduction* / genetics

Substances

MicroRNAs