Prevalence of acute cardiac disorders in patients with suspected ST-segment elevation myocardial infarction and non-significant coronary artery disease

J Electrocardiol. 2014 Jul-Aug;47(4):459-64. doi: 10.1016/j.jelectrocard.2014.04.008. Epub 2014 Apr 18.

Abstract

Background and purpose: We aimed to study the prevalence of acute cardiac disorders in patients with suspected ST-segment elevation myocardial infarction (STEMI) and non-significant coronary artery disease (CAD).

Methods: From January to October 2012 we consecutively included patients admitted with suspected STEMI and non-significant CAD (coronary artery stenosis diameter <50%). Patients were diagnosed with acute cardiac disorder in the presence of elevated cardiac biomarkers (troponin T >50ng/l or creatine kinase MB >4μg/l) or dynamic ECG changes (ST-segment changes or T-wave inversion).

Results: Of the 871 patients admitted with suspected STEMI, 11% (n=95) had non-significant CAD. Of these, 67% (n=64) had elevated cardiac biomarkers or dynamic ECG changes and were accordingly diagnosed with acute cardiac disorders. In the remaining 33% (n=31) of patients, cardiac biomarkers were normal and ECG changes remained stationary.

Conclusions: Acute cardiac disorders were diagnosed in two thirds of patients with suspected STEMI and non-significant CAD.

Keywords: Acute cardiac disorders; Non-significant coronary artery disease; ST-segment elevation myocardial infarction.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Causality
  • Comorbidity
  • Coronary Artery Disease / blood
  • Coronary Artery Disease / diagnosis*
  • Coronary Artery Disease / mortality*
  • Denmark / epidemiology
  • Electrocardiography / statistics & numerical data*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / blood
  • Myocardial Infarction / diagnosis*
  • Myocardial Infarction / mortality*
  • Prevalence
  • Risk Factors
  • Sex Distribution
  • Survival Rate
  • Troponin T / blood*
  • Young Adult

Substances

  • Biomarkers
  • Troponin T