Predictors of memory and processing speed dysfunctions after traumatic brain injury

Biomed Res Int. 2014:2014:129796. doi: 10.1155/2014/129796. Epub 2014 Apr 29.

Abstract

Background: The aims of this study were to evaluate the predictive value of admission Glasgow Coma Scale (GCS) scores, duration of unconsciousness, neurosurgical intervention, and countercoup lesion on the impairment of memory and processing speed functions six months after a traumatic brain injury (TBI) based on a structural equation modeling.

Methods: Thirty TBI patients recruited from Neurosurgical Department at the Kaohsiung Medical University Hospital were administered the Wechsler Memory Scale-III (WMS-III) and the Wechsler Adult Intelligence Scale-III processing speed index to evaluate the memory and processing speed functions.

Results: The study showed that GCS scores accounted for 40% of the variance in memory/processing speed. No significant predictive effects were found for the other three variables. GCS classification at the time of TBI seems to correspond moderately to the severity of memory/processing speed dysfunctions.

Conclusions: The present study demonstrated that admission GCS score is a robust predictor of memory/processing speed dysfunctions after TBI. The results should be replicated with a large sample of patients with TBI, or be extended by examining other potential clinical predictors.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain Injuries* / complications
  • Brain Injuries* / epidemiology
  • Brain Injuries* / physiopathology
  • Brain Injuries* / therapy
  • Coma / complications
  • Coma / epidemiology
  • Coma / physiopathology
  • Coma / therapy
  • Humans
  • Memory Disorders* / epidemiology
  • Memory Disorders* / etiology
  • Memory Disorders* / physiopathology
  • Middle Aged
  • Perceptual Disorders* / epidemiology
  • Perceptual Disorders* / etiology
  • Perceptual Disorders* / physiopathology
  • Time Factors