The realization that Planck-scale physics can be tested with existing technology through the search for spacetime-symmetry violation brought about the development of a comprehensive framework, known as the gravitational standard-model extension (SME), for studying deviations from exact Lorentz and CPT symmetry in nature. The development of this framework and its motivation led to an explosion of new tests of Lorentz symmetry over the past decade and to considerable theoretical interest in the subject. This work reviews the key concepts associated with Lorentz and CPT symmetry, the structure of the SME framework, and some recent experimental and theoretical results.