Abstract
We have designed a novel multifunctional DNA scaffold for the synthesis of fluorescent silver nanoclusters (Ag NCs) using a one-pot approach. The obtained DNA/Ag NCs presented a "light-up" and "spectrum-shift" response to target DNA in vitro and could further image the tumor-related mRNA in living cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Aptamers, Nucleotide / chemistry*
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Cell Survival / drug effects
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Diagnostic Imaging
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Fluorescent Dyes / chemistry*
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HeLa Cells
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Humans
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Mice
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NIH 3T3 Cells
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Nanostructures / chemistry*
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RNA, Messenger / analysis*
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Silver / chemistry*
Substances
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Aptamers, Nucleotide
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Fluorescent Dyes
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RNA, Messenger
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Silver