Renal oncocytosis is a very rare cause of multiple renal masses. Imaging features of renal oncocytosis and combined tumors have rarely been reported. Here, we describe a case of unilateral left renal oncocytosis and a combined hybrid tumor between chromophobe renal cell carcinoma and oncocytoma, which were depicted on CT and MR imaging as multiple enhancing solid masses with one dominant mass. Additionally, we reviewed the literature.