Eco-designed biohybrids based on liposomes, mint-nanosilver and carbon nanotubes for antioxidant and antimicrobial coating

Mater Sci Eng C Mater Biol Appl. 2014 Jun 1:39:177-85. doi: 10.1016/j.msec.2014.02.038. Epub 2014 Mar 5.

Abstract

Noncovalent entities (consisting of liposomes, phyto-nanosilver and carbon nanotubes) with interesting properties were constructed by a "green" bottom-up method. Phytosynthesis of silver nanoparticles using the Mentha piperita extract combines the benefits of this herb with the interesting properties of silver. The obtained silver-based biohybrids showed antioxidant and antimicrobial properties that have been considerable improved in the presence of carbon nanotubes. Thus the eco-designed bioconstructs consisting of cholesterol-containing liposomes, phytonanosilver and carbon nanotubes exhibited high antioxidant activity (AA=90.8%) and have been shown to be strong biocides offering inhibition zone of 25mm against Escherichia coli and 23mm against Staphylococcus aureus and Enterococcus faecalis.

Keywords: Biohybrids; Biomimetic membranes; Carbon nanotubes; Mentha piperita; Silver nanoparticles.

MeSH terms

  • Anti-Infective Agents / chemistry*
  • Antioxidants / chemistry*
  • Escherichia coli / drug effects
  • Liposomes / chemistry*
  • Mentha / chemistry*
  • Metal Nanoparticles / chemistry*
  • Microscopy, Atomic Force
  • Microscopy, Electron, Scanning
  • Nanotubes, Carbon / chemistry*
  • Silver / chemistry
  • Spectroscopy, Fourier Transform Infrared
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Infective Agents
  • Antioxidants
  • Liposomes
  • Nanotubes, Carbon
  • Silver