miR-330-5p targets tyrosinase and induces depigmentation

J Invest Dermatol. 2014 Nov;134(11):2846-2849. doi: 10.1038/jid.2014.231. Epub 2014 May 26.

Authors

Florian Rambow¹, Audrey Bechadergue¹, Gaelle Saintigny², Frédérique Morizot², Christian Mahé², Lionel Larue³

Affiliations

¹ Centre de Recherche, Developmental Genetics of Melanocytes, Institut Curie, Orsay, France; CNRS UMR3347, Orsay, France; INSERM U1021, Orsay, France; Equipe Labellisée-Ligue Nationale Contre le Cancer, Paris, France.
² CHANEL Parfums Beauté, Paris, France.
³ Centre de Recherche, Developmental Genetics of Melanocytes, Institut Curie, Orsay, France; CNRS UMR3347, Orsay, France; INSERM U1021, Orsay, France; Equipe Labellisée-Ligue Nationale Contre le Cancer, Paris, France. Electronic address: lionel.larue@curie.fr.

PMID: 24862846
DOI: 10.1038/jid.2014.231

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

5' Untranslated Regions
Cell Line, Tumor
Humans
Melanocytes / cytology
Melanocytes / metabolism
MicroRNAs / genetics
MicroRNAs / metabolism*
Microphthalmia-Associated Transcription Factor / metabolism*
Monophenol Monooxygenase / metabolism*
Pigmentation / genetics*
RNA, Small Interfering / metabolism

Substances

5' Untranslated Regions
MIRN137 microRNA, human
MIRN330 microRNA, human
MIRN7 microRNA, human
MITF protein, human
MicroRNAs
Microphthalmia-Associated Transcription Factor
RNA, Small Interfering
Monophenol Monooxygenase