Microwave ablation of a large renal aspergilloma

Transpl Infect Dis. 2014 Jun;16(3):496-500. doi: 10.1111/tid.12221. Epub 2014 May 26.

Abstract

Increasing numbers of immunocompromised patients have led to a corresponding rise in the incidence of invasive Aspergillus infections. Despite advances in antifungal therapy coupled with reduction in immunosuppression, invasive aspergillosis is associated with significant morbidity and mortality. Although surgical debulking has proven effective in difficult-to-treat cases, patient comorbidities may prevent such intervention. Non-invasive alternatives to surgery are needed. Microwave ablation has many advantages over other ablative techniques, including convection profile, faster heating time, and higher intra-lesion temperatures, which may be associated with greater therapeutic efficacy. We report a case of microwave ablation as an adjunct to medical therapy in angioinvasive renal aspergilloma.

Keywords: aspergilloma; invasive aspergillosis; liver transplantation; microwave ablation.

Publication types

  • Case Reports

MeSH terms

  • Ablation Techniques / methods*
  • Antifungal Agents / therapeutic use
  • Aspergillosis / drug therapy
  • Aspergillosis / surgery*
  • Humans
  • Kidney Diseases / drug therapy
  • Kidney Diseases / microbiology*
  • Kidney Diseases / surgery*
  • Liver Transplantation / adverse effects*
  • Male
  • Microwaves / therapeutic use*
  • Middle Aged

Substances

  • Antifungal Agents