MM-MTA for direct pulp capping: a histologic comparison with ProRoot MTA in rat molars

J Contemp Dent Pract. 2013 Nov 1;14(6):1019-23. doi: 10.5005/jp-journals-10024-1443.

Abstract

Aim: To compare the histomorphological response of rat dental pulps capped with MM-MTA and ProRoot MTA at 1, 2 and 4 weeks postoperatively.

Materials and methods: Direct pulp capping with MM-MTA and ProRoot MTA, overlaid with light-cured composite resin, was performed on right and left maxillary first molars of 20 Wistar rats. Animals were killed at 1, 2 and 4 weeks postoperatively. Biopsy samples were stained and viewed by light microscopy to determine dentin bridge formation. Data were statistically evaluated with the Kruskal-Wallis test (p < 0.05).

Results: Absence of dentin bridge formation at 1 week, partial dentin bridge formation at 2 weeks and complete dentin bridge formation at 4 weeks are observed with MM-MTA and ProRoot MTA. The results showed no statistically significant difference between both materials at 4 weeks.

Conclusion: Both materials produced similar responses in the pulp when used for pulp capping in intact, caries-free molars of rats.

Publication types

  • Comparative Study

MeSH terms

  • Aluminum Compounds / chemistry
  • Aluminum Compounds / therapeutic use*
  • Animals
  • Calcium Carbonate / chemistry
  • Calcium Carbonate / therapeutic use
  • Calcium Compounds / chemistry
  • Calcium Compounds / therapeutic use*
  • Calcium Sulfate / chemistry
  • Calcium Sulfate / therapeutic use
  • Composite Resins / chemistry
  • Dental Pulp Exposure / therapy
  • Dental Restoration, Permanent / methods
  • Dentin, Secondary / drug effects
  • Dentin, Secondary / pathology
  • Dentin-Bonding Agents / chemistry
  • Drug Combinations
  • Molar / drug effects*
  • Molar / pathology
  • Oxides / chemistry
  • Oxides / therapeutic use*
  • Pulp Capping and Pulpectomy Agents / chemistry
  • Pulp Capping and Pulpectomy Agents / therapeutic use*
  • Rats
  • Rats, Wistar
  • Silicates / chemistry
  • Silicates / therapeutic use*

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Composite Resins
  • Dentin-Bonding Agents
  • Drug Combinations
  • Oxides
  • Pulp Capping and Pulpectomy Agents
  • Silicates
  • mineral trioxide aggregate
  • Calcium Carbonate
  • Calcium Sulfate