Ubiquitin puts actin in its place

Yi-Heng Hao; P Ryan Potts

doi:10.1016/j.molcel.2014.05.014

Ubiquitin puts actin in its place

Mol Cell. 2014 May 22;54(4):544-6. doi: 10.1016/j.molcel.2014.05.014.

Authors

Yi-Heng Hao¹, P Ryan Potts²

Affiliations

¹ Departments of Physiology and Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390-9040, USA.
² Departments of Physiology and Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390-9040, USA. Electronic address: ryan.potts@utsouthwestern.edu.

PMID: 24856219
DOI: 10.1016/j.molcel.2014.05.014

Abstract

In this issue of Molecular Cell, Yuan et al. (2014) report that the Cul3-KLHL20 E3 ubiquitin ligase regulates protein anterograde transport from the trans-Golgi network (TGN) by facilitating localized actin assembly at the TGN through K33-linked ubiquitination of coronin 7.

Publication types

Comment

MeSH terms

Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport / metabolism*
Animals
Carrier Proteins / metabolism*
Cullin Proteins / metabolism*
Humans
Microfilament Proteins / metabolism*
Protein Transport*
Ubiquitin-Protein Ligases / metabolism*

Substances

Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport
Carrier Proteins
Cullin Proteins
KLHL20 protein, human
Microfilament Proteins
coronin proteins
Ubiquitin-Protein Ligases