A tetraphenylethene-based zinc complex as a sensitive DNA probe by coordination interaction

Chem Commun (Camb). 2014 Jul 7;50(53):7060-2. doi: 10.1039/c4cc02172j.

Abstract

We developed a new DNA probe by utilizing the coordination interaction of Zn(2+) with DNA and the consequent emission. Because the coordination interactions do not depend on the length of the DNA, the new probe exhibited much higher sensitivity for the detection of short ssDNA than the corresponding probe based on electrostatic interactions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry
  • DNA Probes / chemistry*
  • DNA, Single-Stranded / chemistry
  • Fluorescent Dyes
  • Oligonucleotides / chemistry
  • Pyridines / chemistry*
  • Static Electricity
  • Stilbenes / chemistry*
  • Zinc / chemistry*

Substances

  • DNA Probes
  • DNA, Single-Stranded
  • Fluorescent Dyes
  • Oligonucleotides
  • Pyridines
  • Stilbenes
  • DNA
  • Zinc