Breast conservation: is the survival better for mastectomy?

J Surg Oncol. 2014 Jul;110(1):58-61. doi: 10.1002/jso.23622. Epub 2014 May 21.

Abstract

Breast conserving therapy with radiation is now firmly established as an effective treatment option for early stage disease, and has been thought for decades to yield equivalent survival outcomes to mastectomy. However, recently published observational studies as well as meta-analyses suggest not only a locoregional, but possibly a systemic benefit to BCT. Choice of surgery and radiation is only one of numerous factors impacting survival following surgery for early stage breast cancer; competing comorbidities and risk of treatment related side effects from radiotherapy must also be considered in order to make optimal treatment recommendations.

Keywords: radiation; therapy; treatment.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / mortality*
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery
  • Combined Modality Therapy
  • Female
  • Humans
  • Mastectomy / mortality*
  • Mastectomy, Segmental / mortality*
  • Radiotherapy
  • Survival Rate