Abstract
A novel sensitive DNA bioassay using lanthanide-doped LiYF4 upconversion nanocrystals as luminescent marker and oligonucleotide hybridization as the selective reaction is developed in a paper-based platform, providing a detection limit of 3.6 fmol.
Keywords:
DNA detection; bioprobes; paper-based; upconversion.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biosensing Techniques*
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DNA / chemistry*
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Lanthanoid Series Elements / chemistry*
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Light
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Limit of Detection
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Luminescence
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Microscopy, Electron, Transmission
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Nanoparticles / chemistry*
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Nanotechnology
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Oligonucleotides / chemistry
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Optics and Photonics
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Paper*
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Photons
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Scattering, Radiation
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Spectroscopy, Near-Infrared
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X-Ray Diffraction
Substances
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Lanthanoid Series Elements
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Oligonucleotides
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DNA