Dorsal subthalamic nucleus electrical stimulation for drug/treatment-refractory epilepsy may modulate melanocortinergic signaling in astrocytes

Epilepsy Behav. 2014 Jul:36:6-8. doi: 10.1016/j.yebeh.2014.04.013. Epub 2014 May 16.

Authors

Bing Ke¹, Tao-Tao Liu², Cheng Liu², Hong-Bing Xiang², Jun Xiong³

Affiliations

¹ Department of Dermatology, Wuhan Central Hospital, Wuhan, Hubei 430010, PR China.
² Department of Anesthesiology and Pain Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China.
³ Hepatobiliary Surgery Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, PR China. Electronic address: xjun1095@163.com.

PMID: 24835897
DOI: 10.1016/j.yebeh.2014.04.013

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Astrocytes / metabolism*
Cerebral Cortex / pathology*
Deep Brain Stimulation / methods*
Disease Models, Animal
Epilepsy / therapy*
Glial Fibrillary Acidic Protein / metabolism
Green Fluorescent Proteins / genetics
Green Fluorescent Proteins / metabolism
Melanocortins / metabolism*
Mice
Mice, Transgenic
Receptor, Melanocortin, Type 4 / genetics
Receptor, Melanocortin, Type 4 / metabolism
Signal Transduction / physiology*
Subthalamic Nucleus / physiology*

Substances

Glial Fibrillary Acidic Protein
MC4R protein, mouse
Melanocortins
Receptor, Melanocortin, Type 4
Green Fluorescent Proteins