Adverse cardiovascular effects from the use of anabolic-androgenic steroids as ergogenic resources

Subst Use Misuse. 2014 Jul;49(9):1132-7. doi: 10.3109/10826084.2014.903751. Epub 2014 May 15.

Abstract

This review evaluates the documented cardiovascular functioning among anabolic-androgenic steroid (AAS) users. AAS users manifest a reduction in HDL cholesterol, increased inflammatory markers, and oxidative stress. Strong evidence associating AAS use with blood pressure at hypertensive levels, as well as hypertrophy and cardiac dysfunction has also been reported. Both epidemiological and autopsy studies attest the relationship between AAS use and early mortality. The review's limitations are noted.

Keywords: anabolic agents; cardiac hypertrophy; cardiovascular diseases; doping in sports; hypertension.

Publication types

  • Review

MeSH terms

  • Anabolic Agents / adverse effects*
  • Androgens / adverse effects*
  • Brain Infarction / diagnosis*
  • Cardiovascular Diseases / chemically induced*
  • Doping in Sports*
  • Dyslipidemias / chemically induced*
  • Humans

Substances

  • Anabolic Agents
  • Androgens