A novel phenolic acid from the fruits of Rosa soulieana

Nat Prod Res. 2014;28(15):1127-33. doi: 10.1080/14786419.2014.915826. Epub 2014 May 15.

Abstract

From the n-BuOH-soluble fraction of a MeOH extract of the fruits of Rosa soulieana, one new phenolic glucoside (1) was isolated along with five known compounds, comprising two lignin glycosides, two flavonoid glycosides and a phenolic glycoside. The chemical structure of the new compound was elucidated by extensive spectroscopic analyses, including ESI-MS, UV, IR, (1)H and (13)C NMR, DEPT and 2D NMR (HSQC and HMBC). All the isolated compounds were evaluated for their antioxidant activity by using ABTS (2,2'-azino-bis(3-ethylbenzoline-6-sulfonic acid)) assay. Among these compounds, 1, 3 and 6 exhibited strong scavenging activity in ABTS(·+)(SC50 = 102.10, 193.85, 65.38 μmol/L, respectively) compared with the positive control l-ascorbic acid (Vc) (SC50 = 117.16 μmol/L).

Keywords: ABTS; Rosa soulieana; antioxidative; phenolic glucoside.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ascorbic Acid / pharmacology
  • Benzothiazoles / pharmacology
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Fruit / chemistry*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Hydroxybenzoates / chemistry
  • Hydroxybenzoates / isolation & purification*
  • Hydroxybenzoates / pharmacology
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Rosa / chemistry*
  • Sulfonic Acids / pharmacology

Substances

  • Benzothiazoles
  • Drugs, Chinese Herbal
  • Glycosides
  • Hydroxybenzoates
  • Sulfonic Acids
  • soulieana acid
  • 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
  • phenolic acid
  • Ascorbic Acid