A one-pot hypoiodite catalysed oxidative cycloetherification approach to benzoxazoles

Chem Commun (Camb). 2014 Jun 28;50(51):6726-8. doi: 10.1039/c4cc02425g.

Abstract

A practical one-pot hypoiodite catalysed oxidative cyclization approach to synthesize α-ketobenzoxazole derivatives was successfully developed. This operationally simple protocol utilizes easily-accessible starting materials and has a broad substrate scope with excellent yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzoxazoles / chemical synthesis*
  • Catalysis
  • Cyclization
  • Ethers / chemical synthesis
  • Indicators and Reagents
  • Iodine Compounds / chemistry*
  • Oxidants / chemistry
  • Oxidation-Reduction

Substances

  • Benzoxazoles
  • Ethers
  • Indicators and Reagents
  • Iodine Compounds
  • Oxidants
  • hypoiodous acid