In the title chromone-tethered benzohydrazide derivative, C20H18N2O6, the atoms of the E-3-(hydrazonometh-yl)-4H-chromen-4-one segment are essentially coplanar, the largest deviation being 0.065 (6) Å. The dihedral angle between this segment and the benzene ring of the tri-meth-oxy-benzene unit is 40.18 (10) Å. In the crystal, the mol-ecule is linked to its inverse-symmetry equivalent by pairs of N-H⋯O hydrogen bonds and C-H⋯π inter-actions. The -CH=N-NH- segment is stacked on the benzene ring of the chromone unit of a translation-related equivalent mol-ecule [centroid-centroid distance = 3.413 (6) Å].