Deciphering developmental processes from single-cell transcriptomes

Paul Robson

doi:10.1016/j.devcel.2014.04.032

Deciphering developmental processes from single-cell transcriptomes

Dev Cell. 2014 May 12;29(3):260-1. doi: 10.1016/j.devcel.2014.04.032.

Author

Paul Robson¹

Affiliation

¹ Developmental Cellomics Laboratory, Genome Institute of Singapore, Singapore 138672; Department of Biological Sciences, National University of Singapore, Singapore 117543. Electronic address: robsonp@gis.a-star.edu.sg.

PMID: 24823374
DOI: 10.1016/j.devcel.2014.04.032

Abstract

Alveoli facilitate air-blood interchange in the lungs from birth to the last breath. Reporting in Nature, Treutlein et al. (2014) apply single-cell RNA sequencing to the developing mouse lung to address some of the unanswered questions surrounding the embryonic origins of alveoli.

Publication types

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MeSH terms

Animals
Cell Lineage / genetics*
Epithelial Cells / cytology*
Epithelial Cells / metabolism*
Female
Lung / cytology*
Sequence Analysis, RNA / methods*
Single-Cell Analysis / methods*