Adrenal insufficiency during treatment for childhood acute lymphoblastic leukemia is associated with glucocorticoid receptor polymorphisms ER22/23EK and BclI

Haematologica. 2014 Aug;99(8):e136-7. doi: 10.3324/haematol.2014.105056. Epub 2014 May 9.
No abstract available

Keywords: ALL; GR polymorphisms; adrenal insufficiency; childhood.

Publication types

  • Letter

MeSH terms

  • Adolescent
  • Adrenal Insufficiency / chemically induced
  • Adrenal Insufficiency / diagnosis*
  • Adrenal Insufficiency / genetics*
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Pilot Projects
  • Polymorphism, Genetic / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Prednisone / adverse effects
  • Receptors, Glucocorticoid / genetics*
  • Treatment Outcome

Substances

  • Receptors, Glucocorticoid
  • Prednisone