A pot experiment was conducted to study the effects of a group matching curing agent (limestone plus sepiolite) with different concentrations (0, 1.0, 2.0, 4.0, 8.0, 16.0 g x kg(-1)) on the exchangeable Pb, Cd, and Zn contents in the potted soil collected from a mining area in southern China and their cumulative distribution in rice plants. The results showed that: (1) Exchangeable Pb, Cd, and Zn contents in the potted soils decreased obviously with the increase in the amounts of group matching curing agent by 15.3%-99.9%, 9.2%-99.9%, and 7.0%-99.9%, respectively, compared with the CK, indicating that the addition of limestone plus sepiolite effectively inhibited the uptake of Pb, Cd, Zn from soils into rice plants. (2) Growth conditions of rice plants were improved, and the heights of rice plants increased with the increase in the amounts of group matching curing agent. The rice yield reached the optimal level and was increased by 60.4% compared with the CK, when the amount of limestone plus sepiolite was 1.0 g x kg(-1). The uptake of heavy metals in different organs of rice plants decreased obviously with the increasing amounts of the group matching curing agent, and the Pb, Cd, and Zn contents of rice grains decreased by 2.2%-13.1%, 29.3%-79.3%, 19.5%-43.3% with different concentrations (1.0-16.0 g x kg(-1)) of the group matching curing agent, respectively, compared with the CK.