Synthesis of β-C-galactosyl ceramide and its new aza variant via the Horner-Wadsworth-Emmons reaction

J Org Chem. 2014 Jun 6;79(11):5193-200. doi: 10.1021/jo500769f. Epub 2014 May 15.

Abstract

A simple strategy for the synthesis of β-C-galactosyl ceramide and its new aza-variant analogue is described using the Horner-Wadsworth-Emmons reaction as the key step in combining the sugar and aglycone portions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aza Compounds / chemical synthesis*
  • Aza Compounds / chemistry*
  • Galactosylceramides / chemical synthesis*
  • Galactosylceramides / chemistry*
  • Molecular Structure
  • Stereoisomerism

Substances

  • Aza Compounds
  • Galactosylceramides