Cell biology: ESCRTing trouble out!

Paul L McNeil

doi:10.1016/j.cub.2014.03.044

Cell biology: ESCRTing trouble out!

Curr Biol. 2014 May 5;24(9):R370-2. doi: 10.1016/j.cub.2014.03.044.

Author

Paul L McNeil¹

Affiliation

¹ Department of Cellular Biology and Anatomy, Georgia Regents University, Augusta, GA 30921, USA. Electronic address: pmcneil@gru.edu.

PMID: 24801189
DOI: 10.1016/j.cub.2014.03.044

Abstract

Calcium entry through a plasma membrane defect leads to the local recruitment of endosomal complex required for transport (ESCRT) proteins. These proteins are hypothesized to drive an outward bending of the affected plasma membrane, forming a small bud that is then shed from the cell, along with the troublesome defect.

Publication types

Comment

MeSH terms

Cell Membrane / metabolism*
Cell Membrane / ultrastructure*
Endosomal Sorting Complexes Required for Transport / metabolism*
Humans

Substances

Endosomal Sorting Complexes Required for Transport