[Research progress of skeletal myoblasts for cardiac repair]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014 Feb;28(2):186-91.
[Article in Chinese]

Abstract

Objective: To review the recent research progress of skeletal myoblasts for cardiac repair.

Methods: The related literature about skeletal myoblasts for cardiac repair was reviewed, analyzed, and summarized.

Results: The results of animal experiments and clinical studies have shown that skeletal myoblasts been transplanted into the regional myocardial infarction area in different ways can improve cardiac function. But there are some challenges such as high loss rate of skeletal myoblasts and resulting in ventricular arrhythmias.

Conclusion: Further studies can improve the safety and effectiveness of skeletal myoblasts for cardiac repair in the future.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Cell Transplantation / adverse effects
  • Cell Transplantation / methods
  • Cell- and Tissue-Based Therapy / methods*
  • Cells, Cultured
  • Humans
  • Myoblasts, Skeletal / cytology
  • Myoblasts, Skeletal / transplantation*
  • Myocardial Infarction / therapy*
  • Myocardial Ischemia / therapy
  • Stem Cell Transplantation* / methods