Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Int J Nanomedicine. 2014 Apr 16:9:1883-9. doi: 10.2147/IJN.S57865. eCollection 2014.

Abstract

New water-soluble nontoxic nanocomposites of nanosized silver particles in a polymer matrix were synthesized by a green chemistry method. Nontoxic poly(1-vinyl-1,2,4-triazole) was used as a stabilizing precursor agent in aqueous medium. Glucose and dimethyl sulfoxide were used as the silver ion-reducing agents to yield silver nanoparticles 2-26 nm and 2-8 nm in size, respectively. The nanocomposites were characterized by transmission electron microscopy, ultraviolet-visible and Fourier transform infrared spectroscopy, X-ray diffraction, atomic absorption, and thermogravimetric data analysis. The nanocomposites showed strong antimicrobial activity against Gram-negative and Gram-positive bacteria.

Keywords: dimethyl sulfoxide; glucose; green synthesis; poly(1-vinyl-1,2,4-triazole); silver nanoparticles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Physiological Phenomena / drug effects*
  • Cell Survival / drug effects
  • Drug Compounding / methods
  • Green Chemistry Technology / methods
  • Materials Testing
  • Metal Nanoparticles / administration & dosage
  • Metal Nanoparticles / chemistry
  • Nanocomposites / administration & dosage*
  • Nanocomposites / chemistry
  • Silver / chemistry*
  • Silver / pharmacology*
  • Solubility
  • Triazoles / chemistry*
  • Water / chemistry*

Substances

  • 1-vinyl-1,2,4-triazole
  • Anti-Bacterial Agents
  • Triazoles
  • Water
  • Silver